Publications

Dr. Rivella was part of a team of researches that discovered suppression of the erythroid iron restriction response by isocitrate administration corrected anemia and erythropoietic defects in rats with ACDI (anemia of chronic disease and inflammation). Published in the Journal of Clinical Investigation on August 2013.

Dr. Rivella was part of a reserach group that discovered using ASOs that targeted Tmprss6, a serine protease, improved anemia and decreased the formation of insoluble globin, ROS, and apoptosis in β-thalassemia mice. Published in the Journal of Clinical Investigation on April 2013.

Dr. Giardina was part a team that researched the effect of deferoxamine and deferiprone on Thalassaemia major patients' heart conditions. Published in Journal of Cardiovascular Magnetic Resonance on 2013.

Dr. Rivella was published in the April 2012 issue of Blood. The role of ineffective erythropoiesis in non-transfusion-dependent thalassemia.

Dr. Rivella was published in the July 2012 issue of Blood. B-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.

Dr. Giardina and Dr. Rivella study hemoglobin levels after gene transfer in mice with thalassemia and patients with thalassemia and sickle cell anemia.

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